Microbial contributions to gut development in the neonatal pig
Willing, Benjamin Peter
The commensal intestinal microbiota contributes substantially to intestinal development in the early neonatal period by mechanisms that are not yet elucidated but could contribute to novel strategies to improve intestinal health. A series of gnotobiotic experiments using isolator-reared caesarian section-derived piglets inoculated at 1 d of age with selected bacteria and euthanized at 14 or 15 days of age were performed to investigate intestinal morphology, inflammation and digestive function. In Experiment 1, piglets were maintained germfree (GF), mono-associated with Escherichia coli (EC), mono-associated with Lactobacillus fermentum (LF) or conventionalized with sow feces (CV). Increased (P
DegreeDoctor of Philosophy (Ph.D.)
DepartmentAnimal and Poultry Science
ProgramAnimal and Poultry Science
SupervisorVan Kessel, Andrew G.
CommitteeSimko, Elemir; Laarveld, Bernard; Buchanan, Fiona C.; Zijlstra, Ruurd T.