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Mass Spectrometric Based Approaches in Urine Metabolomics and Biomarker Discovery
Urine metabolomics has recently emerged as a prominent field for the discovery of non-invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific disease or therapeutic intervention. Urine, ...
Establishment of Tandem Mass Spectrometric Fingerprint of Novel Antineoplastic Curcumin Analogues using Electrospray Ionization
RATIONALE: Curcumin analogues are antineoplastic agents, designed based on the structure of the spice turmeric with structural modifications aiming at enhancing potency. The goal is to identify the common tandem mass ...
Development and validation of fast and simple flow injection analysis-tandem mass spectrometry (FIA-MS/MS) for the determination of metformin in dog serum
A simple, fast and sensitive quantification method for the drug metformin in dog serum was developed using flow injection analysis (FIA)- tandem mass spectrometry (MS/MS). The method was fully validated according to ...